145.3K XNAS Volume
XNAS 18 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Charles J. Casamento | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 22 Oct 2024 | 13,000 | 0 (0%) | 0% | 0 | Common Stock | |
| Charles J. Casamento | Director | Purchase of securities on an exchange or from another person at price $ 2.56 per share. | 09 Sep 2024 | 13,000 | 13,000 (0%) | 0% | 2.6 | 33,280 | Common Stock |
| Sergio Traversa | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 2.71 per share. | 09 Sep 2024 | 55,579 | 299,603 (2%) | 0% | 2.7 | 150,619 | Common Stock |
| Sergio Traversa | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 2.99 per share. | 09 Sep 2024 | 51,407 | 384,024 (2%) | 0% | 3.0 | 153,707 | Common Stock |
| Sergio Traversa | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 2.75 per share. | 09 Sep 2024 | 33,014 | 332,617 (2%) | 0% | 2.8 | 90,789 | Common Stock |
| Maged Shenouda | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 2.55 per share. | 09 Sep 2024 | 8,194 | 43,097 (0%) | 0% | 2.6 | 20,895 | Common Stock |
| Maged Shenouda | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 2.95 per share. | 09 Sep 2024 | 24,120 | 88,335 (0%) | 0% | 3.0 | 71,154 | Common Stock |
| Maged Shenouda | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 2.73 per share. | 09 Sep 2024 | 21,118 | 64,215 (0%) | 0% | 2.7 | 57,652 | Common Stock |
| Paul Kelly | Director | Purchase of securities on an exchange or from another person at price $ 2.59 per share. | 09 Sep 2024 | 25,000 | 212,295 (1%) | 0% | 2.6 | 64,750 | Common Stock |
| Charles J. Casamento | Director | Other type of transaction at price $ 0.00 per share. | 24 May 2024 | 20,976 | 31,522 | - | - | Stock Option (right to buy) | |
| Charles J. Casamento | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2024 | 20,976 | 52,498 | - | - | Stock Option (right to buy) | |
| Sergio Traversa | Director, Chief Executive Officer | Other type of transaction at price $ 0.00 per share. | 24 May 2024 | 122,358 | 183,881 | - | - | Stock Option (right to buy) | |
| Sergio Traversa | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2024 | 122,358 | 306,239 | - | - | Stock Option (right to buy) | |
| Maged Shenouda | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2024 | 54,624 | 136,714 | - | - | Stock Option (right to buy) | |
| Maged Shenouda | Chief Financial Officer | Other type of transaction at price $ 0.00 per share. | 24 May 2024 | 54,624 | 82,090 | - | - | Stock Option (right to buy) | |
| John Glasspool | Director | Other type of transaction at price $ 0.00 per share. | 24 May 2024 | 20,976 | 31,522 | - | - | Stock Option (right to buy) | |
| John Glasspool | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2024 | 20,976 | 52,498 | - | - | Stock Option (right to buy) | |
| Paul Kelly | Director | Other type of transaction at price $ 0.00 per share. | 24 May 2024 | 43,700 | 65,672 | - | - | Stock Option (right to buy) | |
| Paul Kelly | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2024 | 43,700 | 109,372 | - | - | Stock Option (right to buy) | |
| Charles S. Ence | CA and CO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2024 | 54,624 | 136,714 | - | - | Stock Option (right to buy) | |
| Charles S. Ence | CA and CO | Other type of transaction at price $ 0.00 per share. | 24 May 2024 | 54,624 | 82,090 | - | - | Stock Option (right to buy) | |
| Fabiana Fedeli | Director | Other type of transaction at price $ 0.00 per share. | 24 May 2024 | 20,976 | 31,522 | - | - | Stock Option (right to buy) | |
| Fabiana Fedeli | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2024 | 20,976 | 52,498 | - | - | Stock Option (right to buy) | |
| Traversa Sergio | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 3.71 per share. | 29 Jan 2024 | 31,541 | 175,565 (1%) | 0% | 3.7 | 117,036 | Common Stock |
| Ence Charles S. | CA and CO | Purchase of securities on an exchange or from another person at price $ 3.87 per share. | 29 Jan 2024 | 14,500 | 25,300 (0%) | 0% | 3.9 | 56,053 | Common Stock |
| Shenouda Maged | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 3.89 per share. | 29 Jan 2024 | 15,000 | 28,028 (0%) | 0% | 3.9 | 58,323 | Common Stock |
| Charles Ence S. | CA and CO | Purchase of securities on an exchange or from another person at price $ 3.65 per share. | 29 Jan 2024 | 10,800 | 10,800 (0%) | 0% | 3.7 | 39,438 | Common Stock |
| Maged Shenouda | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 4.06 per share. | 29 Jan 2024 | 6,875 | 34,903 (0%) | 0% | 4.1 | 27,943 | Common Stock |
| Charles S. Ence | CA and CO | Purchase of securities on an exchange or from another person at price $ 4.05 per share. | 29 Jan 2024 | 13,670 | 38,970 (0%) | 0% | 4.1 | 55,429 | Common Stock |
| Shenouda Maged | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 3.65 per share. | 29 Jan 2024 | 10,800 | 13,028 (0%) | 0% | 3.7 | 39,450 | Common Stock |
| Traversa Sergio | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 3.90 per share. | 29 Jan 2024 | 40,999 | 216,564 (1%) | 0% | 3.9 | 159,949 | Common Stock |
| Traversa Sergio | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 4.00 per share. | 29 Jan 2024 | 27,460 | 244,024 (1%) | 0% | 4.0 | 109,752 | Common Stock |
| Ence S. Charles | Chief Accounting and CO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2023 | 82,090 | 82,090 | - | - | Stock Option (right to buy) | |
| Fabiana Fedeli | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2023 | 31,522 | 31,522 | - | - | Stock Option (right to buy) | |
| Kelly Paul | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2023 | 65,672 | 65,672 | - | - | Stock Option (right to buy) | |
| Casamento Charles J. | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2023 | 31,522 | 31,522 | - | - | Stock Option (right to buy) | |
| John Glasspool | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2023 | 31,522 | 31,522 | - | - | Stock Option (right to buy) | |
| Shenouda Maged | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2023 | 82,090 | 82,090 | - | - | Stock Option (right to buy) | |
| Traversa Sergio | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2023 | 183,881 | 183,881 | - | - | Stock Option (right to buy) | |
| Charles J. Casamento | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 92,958 | 150,000 | - | - | Stock Option (right to buy) | |
| Sergio Traversa | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 527,211 | 850,728 | - | - | Stock Option (right to buy) | |
| Maged Shenouda | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 317,643 | 512,560 | - | - | Stock Option (right to buy) | |
| John Glasspool | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 92,958 | 150,000 | - | - | Stock Option (right to buy) | |
| Paul Kelly | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 92,958 | 150,000 | - | - | Stock Option (right to buy) | |
| Charles S. Ence | CA and CO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 321,238 | 518,361 | - | - | Stock Option (right to buy) | |
| Eric Schmidt | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 92,958 | 150,000 | - | - | Stock Option (right to buy) | |
| Fabiana Fedeli | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 200,000 | 200,000 | - | - | Stock Option (right to buy) | |
| Cedric O'Gorman | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 3.18 per share. | 23 May 2023 | 10,000 | 10,121 (0%) | 0% | 3.2 | 31,800 | Common Stock |
| Cedric O'Gorman | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2023 | 400,000 | 400,000 | - | - | Stock Option (right to buy) | |
| Charles J. Casamento | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 10,000 | 0 (0%) | 0% | 0 | Common Stock | |
| Charles J. Casamento | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 10,000 | 10,000 (0%) | 0% | 0 | Common Stock | |
| Sergio Traversa | Director, CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 4,131 | 0 | - | - | Stock Option (right to buy) | |
| Sergio Traversa | Director, CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 87,500 | 162,500 | - | - | Stock Option (right to buy) | |
| Sergio Traversa | Director, CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 62,500 | 162,500 | - | - | Stock Option (right to buy) | |
| Sergio Traversa | Director, CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 31,250 | 225,000 | - | - | Stock Option (right to buy) | |
| Sergio Traversa | Director, CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 131,250 | 218,750 | - | - | Stock Option (right to buy) | |
| Sergio Traversa | Director, CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 8,231 | 3,019 | - | - | Stock Option (right to buy) | |
| Sergio Traversa | Director, CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 27,123 | 6,165 | - | - | Stock Option (right to buy) | |
| Paul Kelly | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 19,600 | 130,400 | - | - | Stock Option (right to buy) | |
| Paul Kelly | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 56,000 | 94,000 | - | - | Stock Option (right to buy) | |
| Paul Kelly | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 18,000 | 132,000 | - | - | Stock Option (right to buy) | |
| Paul Kelly | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 6,400 | 41 | - | - | Stock Option (right to buy) | |
| Charles J. Casamento | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2022 | 57,042 | 57,042 | - | - | Stock Option (right to buy) | |
| Sergio Traversa | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2022 | 323,517 | 323,517 | - | - | Stock Option (right to buy) | |
| Sergio Traversa | Director, Chief Executive Officer | Other type of transaction at price $ 0.00 per share. | 16 Dec 2022 | 300,000 | 0 | - | - | Stock Option (right to buy) | |
| Maged Shenouda | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2022 | 194,917 | 194,917 | - | - | Stock Option (right to buy) | |
| Maged Shenouda | CFO | Other type of transaction at price $ 0.00 per share. | 16 Dec 2022 | 200,000 | 0 | - | - | Stock Option (right to buy) | |
| John Glasspool | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2022 | 57,042 | 57,042 | - | - | Stock Option (right to buy) | |
| Paul Kelly | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2022 | 57,042 | 57,042 | - | - | Stock Option (right to buy) | |
| Charles S. Ence | CA and Compliance Officer | Other type of transaction at price $ 0.00 per share. | 16 Dec 2022 | 200,000 | 0 | - | - | Stock Option (right to buy) | |
| Charles S. Ence | CA and CO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2022 | 197,123 | 197,123 | - | - | Stock Option (right to buy) | |
| Eric Schmidt | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2022 | 57,042 | 57,042 | - | - | Stock Option (right to buy) | |
| Sergio Traversa | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 2.10 per share. | 08 Dec 2022 | 55,250 | 144,024 (0%) | 0% | 2.1 | 115,804 | Common Stock |
| Sergio Traversa | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2022 | 13,755 | 0 | - | - | Stock Option (right to buy) | |
| Sergio Traversa | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 30 Jun 2022 | 16,012 | 104,786 (0%) | 0% | 16 | 256,192 | Common Stock |
| Sergio Traversa | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 19.37 per share. | 30 Jun 2022 | 5,314 | 99,472 (0%) | 0% | 19.4 | 102,932 | Common Stock |
| Sergio Traversa | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 19.01 per share. | 30 Jun 2022 | 10,698 | 88,774 (0%) | 0% | 19.0 | 203,369 | Common Stock |
| Sergio Traversa | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 30 Jun 2022 | 13,755 | 102,529 (0%) | 0% | 16 | 220,080 | Common Stock |
| Sergio Traversa | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 18.48 per share. | 30 Jun 2022 | 839 | 101,690 (0%) | 0% | 18.5 | 15,505 | Common Stock |
| Sergio Traversa | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 18.45 per share. | 30 Jun 2022 | 8,848 | 92,842 (0%) | 0% | 18.5 | 163,246 | Common Stock |
| Sergio Traversa | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 18.32 per share. | 30 Jun 2022 | 4,068 | 88,774 (0%) | 0% | 18.3 | 74,526 | Common Stock |
| Sergio Traversa | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2022 | 16,012 | 13,755 | - | - | Stock Option (right to buy) | |
| Sergio Traversa | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2022 | 300,000 | 300,000 | - | - | Stock Option (right to buy) | |
| Sergio Traversa | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2022 | 651,821 | 1,143,994 | - | - | Stock Option (right to buy) | |
| Maged Shenouda | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2022 | 295,211 | 522,729 | - | - | Stock Option (right to buy) | |
| Maged Shenouda | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2022 | 200,000 | 200,000 | - | - | Stock Option (right to buy) | |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 04 Apr 2022 | 10,000 | 197,295 (1%) | 0% | 3.2 | 32,400 | Common Stock |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Apr 2022 | 10,000 | 20,500 | - | - | Options to purchase common stock | |
| Paul Kelly | Director | Sale of securities on an exchange or to another person at price $ 30.04 per share. | 04 Apr 2022 | 10,000 | 187,295 (1%) | 0% | 30.0 | 300,395 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 29.00 per share. | 01 Apr 2022 | 3,300 | 3,300 (0%) | 0% | 29 | 95,700 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 29.00 per share. | 01 Apr 2022 | 3,300 | 6,600 (0%) | 0% | 29 | 95,700 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 29.00 per share. | 01 Apr 2022 | 3,300 | 9,900 (0%) | 0% | 29 | 95,700 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 29.00 per share. | 01 Apr 2022 | 3,300 | 13,200 (0%) | 0% | 29 | 95,700 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 29.00 per share. | 01 Apr 2022 | 3,300 | 16,500 (0%) | 0% | 29 | 95,700 | Common Stock |
| Charles J. Casamento | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 01 Apr 2022 | 19,800 | 19,800 (0%) | 0% | 3.2 | 64,152 | Common Stock |
| Charles J. Casamento | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Apr 2022 | 19,800 | 77,511 | - | - | Stock Option (right to buy) | |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 29.00 per share. | 01 Apr 2022 | 3,300 | 0 (0%) | 0% | 29 | 95,700 | Common Stock |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jan 2022 | 20,000 | 30,500 | - | - | Options to purchase common stock | |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 03 Jan 2022 | 20,000 | 187,295 (1%) | 0% | 3.2 | 64,800 | Common Stock |
| Charles J. Casamento | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2021 | 58,765 | 58,765 | - | - | Stock Option (right to buy) | |
| Sergio Traversa | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2021 | 492,173 | 492,173 | - | - | Stock Option (right to buy) | |
| Maged Shenouda | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2021 | 227,518 | 227,518 | - | - | Stock Option (right to buy) | |
| John Glasspool | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2021 | 58,765 | 58,765 | - | - | Stock Option (right to buy) | |
| Paul Kelly | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2021 | 117,530 | 117,530 | - | - | Stock Option (right to buy) | |
| Charles S. Ence | CAO and Compliance Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2021 | 226,832 | 226,832 | - | - | Stock Option (right to buy) | |
| Eric Schmidt | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2021 | 58,765 | 58,765 | - | - | Stock Option (right to buy) | |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 29.00 per share. | 22 Sep 2021 | 1,900 | 14,700 (0%) | 0% | 29 | 55,100 | Common Stock |
| Charles J. Casamento | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Sep 2021 | 1,900 | 97,311 | - | - | Options to purchase common stock | |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 29.00 per share. | 22 Sep 2021 | 1,400 | 10,000 (0%) | 0% | 29 | 40,600 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 29.00 per share. | 22 Sep 2021 | 3,300 | 11,400 (0%) | 0% | 29 | 95,700 | Common Stock |
| Charles J. Casamento | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.60 per share. | 22 Sep 2021 | 10,000 | 16,600 (0%) | 0% | 4.6 | 46,000 | Common Stock |
| Charles J. Casamento | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Aug 2021 | 10,000 | 102,500 | - | - | Options to purchase common stock | |
| Charles J. Casamento | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.60 per share. | 17 Aug 2021 | 10,000 | 14,700 (0%) | 0% | 4.6 | 46,000 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 31.03 per share. | 15 Jul 2021 | 2,136 | 5,854 (0%) | 0% | 31.0 | 66,272 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 32.49 per share. | 15 Jul 2021 | 1,164 | 4,700 (0%) | 0% | 32.5 | 37,816 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 33.19 per share. | 01 Jun 2021 | 2,480 | 6,950 (0%) | 0% | 33.2 | 82,300 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 34.08 per share. | 01 Jun 2021 | 520 | 9,430 (0%) | 0% | 34.1 | 17,721 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 38.22 per share. | 03 May 2021 | 3,000 | 9,950 (0%) | 0% | 38.2 | 114,647 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 35.04 per share. | 01 Apr 2021 | 1,691 | 12,950 (0%) | 0% | 35.0 | 59,253 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 35.93 per share. | 01 Apr 2021 | 1,309 | 14,641 (0%) | 0% | 35.9 | 47,028 | Common Stock |
| Sergio Traversa | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Mar 2021 | 10,000 | 99,211 | - | - | Options to purchase common stock | |
| Sergio Traversa | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 09 Mar 2021 | 10,000 | 98,774 (0%) | 0% | 3.2 | 32,400 | Common Stock |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 35.42 per share. | 09 Mar 2021 | 5,217 | 93,937 (0%) | 0% | 35.4 | 184,789 | Common Stock |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 36.32 per share. | 09 Mar 2021 | 1,800 | 91,757 (0%) | 0% | 36.3 | 65,380 | Common Stock |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 35.09 per share. | 09 Mar 2021 | 2,983 | 88,774 (0%) | 0% | 35.1 | 104,676 | Common Stock |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Mar 2021 | 5,000 | 50,500 | - | - | Options to purchase common stock | |
| Paul Kelly | Director | Sale of securities on an exchange or to another person at price $ 36.33 per share. | 09 Mar 2021 | 1,612 | 167,295 (1%) | 0% | 36.3 | 58,556 | Common Stock |
| Paul Kelly | Director | Sale of securities on an exchange or to another person at price $ 35.42 per share. | 09 Mar 2021 | 3,388 | 168,907 (1%) | 0% | 35.4 | 119,995 | Common Stock |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 09 Mar 2021 | 5,000 | 172,295 (1%) | 0% | 3.2 | 16,200 | Common Stock |
| Maged Shenouda | CFO | Sale of securities on an exchange or to another person at price $ 36.02 per share. | 08 Mar 2021 | 1,800 | 4,601 (0%) | 0% | 36.0 | 64,836 | Common Stock |
| Maged Shenouda | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Mar 2021 | 10,000 | 70,350 | - | - | Options to purchase common stock | |
| Maged Shenouda | CFO | Sale of securities on an exchange or to another person at price $ 35.11 per share. | 08 Mar 2021 | 2,373 | 2,228 (0%) | 0% | 35.1 | 83,313 | Common Stock |
| Maged Shenouda | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 08 Mar 2021 | 10,000 | 12,228 (0%) | 0% | 3.2 | 32,400 | Common Stock |
| Maged Shenouda | CFO | Sale of securities on an exchange or to another person at price $ 35.42 per share. | 08 Mar 2021 | 5,727 | 6,401 (0%) | 0% | 35.4 | 202,857 | Common Stock |
| Maged Shenouda | CFO | Sale of securities on an exchange or to another person at price $ 35.00 per share. | 08 Mar 2021 | 100 | 12,128 (0%) | 0% | 35 | 3,500 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 33.87 per share. | 01 Mar 2021 | 3,000 | 15,950 (0%) | 0% | 33.9 | 101,618 | Common Stock |
| Sergio Traversa | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 24 Feb 2021 | 10,000 | 98,774 (0%) | 0% | 3.2 | 32,400 | Common Stock |
| Sergio Traversa | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Feb 2021 | 10,000 | 109,211 | - | - | Options to purchase common stock | |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 35.55 per share. | 24 Feb 2021 | 303 | 88,774 (0%) | 0% | 35.5 | 10,771 | Common Stock |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 34.70 per share. | 24 Feb 2021 | 4,860 | 89,077 (0%) | 0% | 34.7 | 168,659 | Common Stock |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 33.69 per share. | 24 Feb 2021 | 4,837 | 93,937 (0%) | 0% | 33.7 | 162,963 | Common Stock |
| Maged Shenouda | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Feb 2021 | 3,000 | 80,250 | - | - | Options to purchase common stock | |
| Maged Shenouda | CFO | Sale of securities on an exchange or to another person at price $ 34.67 per share. | 24 Feb 2021 | 1,400 | 2,228 (0%) | 0% | 34.7 | 48,544 | Common Stock |
| Maged Shenouda | CFO | Sale of securities on an exchange or to another person at price $ 33.74 per share. | 24 Feb 2021 | 1,600 | 3,628 (0%) | 0% | 33.7 | 53,985 | Common Stock |
| Maged Shenouda | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 24 Feb 2021 | 3,000 | 5,228 (0%) | 0% | 3.2 | 9,720 | Common Stock |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 24 Feb 2021 | 5,000 | 172,295 (1%) | 0% | 3.2 | 16,200 | Common Stock |
| Paul Kelly | Director | Sale of securities on an exchange or to another person at price $ 33.67 per share. | 24 Feb 2021 | 2,429 | 169,866 (1%) | 0% | 33.7 | 81,775 | Common Stock |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Feb 2021 | 5,000 | 55,500 | - | - | Options to purchase common stock | |
| Paul Kelly | Director | Sale of securities on an exchange or to another person at price $ 35.58 per share. | 24 Feb 2021 | 108 | 167,295 (1%) | 0% | 35.6 | 3,843 | Common Stock |
| Paul Kelly | Director | Sale of securities on an exchange or to another person at price $ 34.64 per share. | 24 Feb 2021 | 2,463 | 167,403 (1%) | 0% | 34.6 | 85,315 | Common Stock |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Feb 2021 | 5,000 | 20,000 | - | - | Warrants | |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.00 per share. | 16 Feb 2021 | 5,000 | 167,295 (1%) | 0% | 6 | 30,000 | Common Stock |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 35.43 per share. | 11 Feb 2021 | 1,446 | 88,774 (0%) | 0% | 35.4 | 51,238 | Common Stock |
| Sergio Traversa | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Feb 2021 | 1,446 | 119,211 | - | - | Options to purchase common stock | |
| Sergio Traversa | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 11 Feb 2021 | 1,446 | 90,220 (0%) | 0% | 3.2 | 4,685 | Common Stock |
| Maged Shenouda | CFO | Sale of securities on an exchange or to another person at price $ 35.39 per share. | 11 Feb 2021 | 1,428 | 2,228 (0%) | 0% | 35.4 | 50,542 | Common Stock |
| Maged Shenouda | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Feb 2021 | 1,428 | 83,250 | - | - | Options to purchase common stock | |
| Maged Shenouda | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 11 Feb 2021 | 1,428 | 3,656 (0%) | 0% | 3.2 | 4,627 | Common Stock |
| Sergio Traversa | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 08 Feb 2021 | 11,206 | 99,980 (0%) | 0% | 3.2 | 36,307 | Common Stock |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 35.03 per share. | 08 Feb 2021 | 3,313 | 96,667 (0%) | 0% | 35.0 | 116,049 | Common Stock |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 35.21 per share. | 08 Feb 2021 | 5,963 | 90,704 (0%) | 0% | 35.2 | 209,939 | Common Stock |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 35.28 per share. | 08 Feb 2021 | 1,930 | 88,774 (0%) | 0% | 35.3 | 68,097 | Common Stock |
| Sergio Traversa | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Feb 2021 | 11,206 | 120,657 | - | - | Options to purchase common stock | |
| Maged Shenouda | CFO | Sale of securities on an exchange or to another person at price $ 35.04 per share. | 08 Feb 2021 | 3,603 | 9,997 (0%) | 0% | 35.0 | 126,242 | Common Stock |
| Maged Shenouda | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 08 Feb 2021 | 11,372 | 13,600 (0%) | 0% | 3.2 | 36,845 | Common Stock |
| Maged Shenouda | CFO | Sale of securities on an exchange or to another person at price $ 35.24 per share. | 08 Feb 2021 | 5,359 | 4,638 (0%) | 0% | 35.2 | 188,843 | Common Stock |
| Maged Shenouda | CFO | Sale of securities on an exchange or to another person at price $ 35.20 per share. | 08 Feb 2021 | 2,410 | 2,228 (0%) | 0% | 35.2 | 84,825 | Common Stock |
| Maged Shenouda | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Feb 2021 | 11,372 | 84,678 | - | - | Options to purchase common stock | |
| Paul Kelly | Director | Sale of securities on an exchange or to another person at price $ 35.04 per share. | 08 Feb 2021 | 1,500 | 164,364 (1%) | 0% | 35.0 | 52,560 | Common Stock |
| Paul Kelly | Director | Sale of securities on an exchange or to another person at price $ 35.29 per share. | 08 Feb 2021 | 2,069 | 162,295 (1%) | 0% | 35.3 | 73,005 | Common Stock |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Feb 2021 | 3,569 | 60,500 | - | - | Options to purchase common stock | |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 08 Feb 2021 | 3,569 | 165,864 (1%) | 0% | 3.2 | 11,564 | Common Stock |
| Sergio Traversa | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Feb 2021 | 3,278 | 145,144 | - | - | Options to purchase common stock | |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 35.08 per share. | 02 Feb 2021 | 3,178 | 88,874 (0%) | 0% | 35.1 | 111,470 | Common Stock |
| Sergio Traversa | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 02 Feb 2021 | 3,278 | 92,052 (0%) | 0% | 3.2 | 10,621 | Common Stock |
| Sergio Traversa | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Feb 2021 | 13,281 | 131,863 | - | - | Options to purchase common stock | |
| Sergio Traversa | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 02 Feb 2021 | 13,281 | 88,774 (0%) | 0% | 3.2 | 43,030 | Common Stock |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 35.00 per share. | 02 Feb 2021 | 100 | 88,874 (0%) | 0% | 35 | 3,500 | Common Stock |
| Maged Shenouda | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 02 Feb 2021 | 3,200 | 5,428 (0%) | 0% | 3.2 | 10,368 | Common Stock |
| Maged Shenouda | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Feb 2021 | 3,200 | 96,050 | - | - | Options to purchase common stock | |
| Maged Shenouda | CFO | Sale of securities on an exchange or to another person at price $ 35.00 per share. | 02 Feb 2021 | 100 | 2,228 (0%) | 0% | 35 | 3,500 | Common Stock |
| Maged Shenouda | CFO | Sale of securities on an exchange or to another person at price $ 35.04 per share. | 02 Feb 2021 | 3,100 | 2,328 (0%) | 0% | 35.0 | 108,634 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 33.90 per share. | 01 Feb 2021 | 1,663 | 18,950 (0%) | 0% | 33.9 | 56,376 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 33.30 per share. | 01 Feb 2021 | 1,337 | 20,613 (0%) | 0% | 33.3 | 44,522 | Common Stock |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Feb 2021 | 2,346 | 64,069 | - | - | Options to purchase common stock | |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Feb 2021 | 15,000 | 66,415 | - | - | Options to purchase common stock | |
| Paul Kelly | Director | Sale of securities on an exchange or to another person at price $ 35.04 per share. | 01 Feb 2021 | 2,315 | 162,295 (1%) | 0% | 35.0 | 81,118 | Common Stock |
| Paul Kelly | Director | Sale of securities on an exchange or to another person at price $ 35.00 per share. | 01 Feb 2021 | 31 | 164,610 (1%) | 0% | 35 | 1,085 | Common Stock |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 01 Feb 2021 | 2,346 | 164,641 (1%) | 0% | 3.2 | 7,601 | Common Stock |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 01 Feb 2021 | 15,000 | 162,295 (1%) | 0% | 3.2 | 48,600 | Common Stock |
| Sergio Traversa | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 27 Jan 2021 | 10,000 | 85,493 (0%) | 0% | 3.2 | 32,400 | Common Stock |
| Sergio Traversa | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jan 2021 | 10,000 | 148,422 | - | - | Options to purchase common stock | |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 33.43 per share. | 27 Jan 2021 | 100 | 75,493 (0%) | 0% | 33.4 | 3,343 | Common Stock |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 32.86 per share. | 27 Jan 2021 | 5,549 | 75,593 (0%) | 0% | 32.9 | 182,340 | Common Stock |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 31.77 per share. | 27 Jan 2021 | 4,351 | 81,142 (0%) | 0% | 31.8 | 138,231 | Common Stock |
| Maged Shenouda | CFO | Sale of securities on an exchange or to another person at price $ 31.59 per share. | 27 Jan 2021 | 1,800 | 3,428 (0%) | 0% | 31.6 | 56,862 | Common Stock |
| Maged Shenouda | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jan 2021 | 3,000 | 99,250 | - | - | Options to purchase common stock | |
| Maged Shenouda | CFO | Sale of securities on an exchange or to another person at price $ 32.43 per share. | 27 Jan 2021 | 1,200 | 2,228 (0%) | 0% | 32.4 | 38,916 | Common Stock |
| Maged Shenouda | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 27 Jan 2021 | 3,000 | 5,228 (0%) | 0% | 3.2 | 9,720 | Common Stock |
| Paul Kelly | Director | Sale of securities on an exchange or to another person at price $ 31.69 per share. | 27 Jan 2021 | 1,844 | 150,451 (1%) | 0% | 31.7 | 58,436 | Common Stock |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jan 2021 | 5,000 | 81,415 | - | - | Options to purchase common stock | |
| Paul Kelly | Director | Sale of securities on an exchange or to another person at price $ 33.40 per share. | 27 Jan 2021 | 168 | 147,295 (1%) | 0% | 33.4 | 5,611 | Common Stock |
| Paul Kelly | Director | Sale of securities on an exchange or to another person at price $ 32.89 per share. | 27 Jan 2021 | 2,988 | 147,463 (1%) | 0% | 32.9 | 98,275 | Common Stock |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 27 Jan 2021 | 5,000 | 152,295 (1%) | 0% | 3.2 | 16,200 | Common Stock |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 35.15 per share. | 22 Jan 2021 | 600 | 75,493 (0%) | 0% | 35.2 | 21,090 | Common Stock |
| Sergio Traversa | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Jan 2021 | 4,070 | 158,422 | - | - | Options to purchase common stock | |
| Sergio Traversa | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 22 Jan 2021 | 4,070 | 79,563 (0%) | 0% | 3.2 | 13,187 | Common Stock |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 35.44 per share. | 22 Jan 2021 | 1,736 | 77,827 (0%) | 0% | 35.4 | 61,524 | Common Stock |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 36.15 per share. | 22 Jan 2021 | 434 | 77,393 (0%) | 0% | 36.1 | 15,689 | Common Stock |
| Sergio Traversa | Director, CEO | Sale of securities on an exchange or to another person at price $ 35.29 per share. | 22 Jan 2021 | 1,300 | 76,093 (0%) | 0% | 35.3 | 45,877 | Common Stock |
| Maged Shenouda | CFO | Sale of securities on an exchange or to another person at price $ 35.16 per share. | 22 Jan 2021 | 607 | 2,228 (0%) | 0% | 35.2 | 21,342 | Common Stock |
| Maged Shenouda | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 22 Jan 2021 | 4,000 | 6,228 (0%) | 0% | 3.2 | 12,960 | Common Stock |
| Maged Shenouda | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Jan 2021 | 4,000 | 102,250 | - | - | Options to purchase common stock | |
| Maged Shenouda | CFO | Sale of securities on an exchange or to another person at price $ 35.27 per share. | 22 Jan 2021 | 1,280 | 2,835 (0%) | 0% | 35.3 | 45,146 | Common Stock |
| Maged Shenouda | CFO | Sale of securities on an exchange or to another person at price $ 36.15 per share. | 22 Jan 2021 | 409 | 4,115 (0%) | 0% | 36.1 | 14,785 | Common Stock |
| Maged Shenouda | CFO | Sale of securities on an exchange or to another person at price $ 35.41 per share. | 22 Jan 2021 | 1,704 | 4,524 (0%) | 0% | 35.4 | 60,339 | Common Stock |
| Maged Shenouda | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 324.00 per share. | 22 Jan 2021 | 4,000 | 6,228 (0%) | 0% | 324 | 1,296,000 | Common Stock |
| Paul Kelly | Director | Sale of securities on an exchange or to another person at price $ 35.16 per share. | 22 Jan 2021 | 685 | 147,295 (1%) | 0% | 35.2 | 24,085 | Common Stock |
| Paul Kelly | Director | Sale of securities on an exchange or to another person at price $ 35.43 per share. | 22 Jan 2021 | 1,800 | 149,580 (1%) | 0% | 35.4 | 63,774 | Common Stock |
| Paul Kelly | Director | Sale of securities on an exchange or to another person at price $ 3543.00 per share. | 22 Jan 2021 | 1,800 | 149,580 (1%) | 0% | 3543 | 6,377,400 | Common Stock |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 22 Jan 2021 | 4,085 | 151,380 (1%) | 0% | 3.2 | 13,235 | Common Stock |
| Paul Kelly | Director | Sale of securities on an exchange or to another person at price $ 36.18 per share. | 22 Jan 2021 | 300 | 149,280 (1%) | 0% | 36.2 | 10,854 | Common Stock |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Jan 2021 | 4,085 | 86,415 | - | - | Options to purchase common stock | |
| Paul Kelly | Director | Sale of securities on an exchange or to another person at price $ 35.27 per share. | 22 Jan 2021 | 1,300 | 147,980 (1%) | 0% | 35.3 | 45,851 | Common Stock |
| Charles J. Casamento | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2021 | 100,000 | 100,000 | - | - | Options to purchase common stock | |
| Sergio Traversa | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2021 | 250,000 | 250,000 | - | - | Options to purchase common stock | |
| Sergio Traversa | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2021 | 250,000 | 250,000 | - | - | Options to purchase common stock | |
| Maged Shenouda | CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2021 | 127,500 | 127,500 | - | - | Options to purchase common stock | |
| Maged Shenouda | CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2021 | 127,500 | 127,500 | - | - | Options to purchase common stock | |
| John Glasspool | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2021 | 100,000 | 100,000 | - | - | Options to purchase common stock | |
| Paul Kelly | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2021 | 150,000 | 150,000 | - | - | Options to purchase common stock | |
| Charles S. Ence | Chief Compliance Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2021 | 112,500 | 112,500 | - | - | Options to purchase common stock | |
| Charles S. Ence | Chief Compliance Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2021 | 112,500 | 112,500 | - | - | Options to purchase common stock | |
| Eric Schmidt | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2021 | 100,000 | 100,000 | - | - | Options to purchase common stock | |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 32.11 per share. | 04 Jan 2021 | 3,000 | 21,950 (0%) | 0% | 32.1 | 96,342 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 35.74 per share. | 24 Nov 2020 | 3,000 | 24,950 (0%) | 0% | 35.7 | 107,219 | Common Stock |
| Charles J. Casamento | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 24 Nov 2020 | 21,223 | 27,950 (0%) | 0% | 0 | Common Stock | |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 30.29 per share. | 02 Nov 2020 | 3,000 | 49,173 (0%) | 0% | 30.3 | 90,864 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 37.99 per share. | 01 Oct 2020 | 3,000 | 52,173 (0%) | 0% | 38.0 | 113,956 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 34.74 per share. | 01 Sep 2020 | 3,000 | 55,173 (0%) | 0% | 34.7 | 104,207 | Common Stock |
| Charles J. Casamento | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 39.03 per share. | 18 Aug 2020 | 2,189 | 58,173 (0%) | 0% | 39.0 | 85,437 | Common Stock |
| Charles J. Casamento | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 18 Aug 2020 | 26,362 | 60,362 (0%) | 0% | 3.2 | 85,413 | Common Stock |
| Charles J. Casamento | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Aug 2020 | 26,362 | 33,404 | - | - | Options to purchase common stock | |
| Sergio Traversa | Director, CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 39.03 per share. | 18 Aug 2020 | 4,151 | 75,493 (0%) | 0% | 39.0 | 162,014 | Common Stock |
| Sergio Traversa | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Aug 2020 | 50,008 | 162,492 | - | - | Options to purchase common stock | |
| Sergio Traversa | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 18 Aug 2020 | 50,008 | 79,644 (0%) | 0% | 3.2 | 162,026 | Common Stock |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Aug 2020 | 22,000 | 90,500 | - | - | Options to purchase common stock | |
| Paul Kelly | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 39.03 per share. | 18 Aug 2020 | 1,826 | 147,295 (1%) | 0% | 39.0 | 71,269 | Common Stock |
| Paul Kelly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.24 per share. | 18 Aug 2020 | 22,000 | 149,121 (1%) | 0% | 3.2 | 71,280 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 35.74 per share. | 03 Aug 2020 | 3,000 | 34,000 (0%) | 0% | 35.7 | 107,213 | Common Stock |
| Charles J. Casamento | Director | Sale of securities on an exchange or to another person at price $ 43.89 per share. | 01 Jul 2020 | 3,000 | 37,000 (0%) | 0% | 43.9 | 131,677 | Common Stock |
| Eric Schmidt | Director | 09 Apr 2020 | 32,500 | 87,500 (0%) | 0% | 6 | 195,000 | Common Stock | |
| Eric Schmidt | Director | 09 Apr 2020 | 12,500 | 0 | - | - | Warrants to purchase common stock | ||
| Eric Schmidt | Director | 09 Apr 2020 | 32,500 | 0 | - | - | Warrants to purchase common stock | ||
| Eric Schmidt | Director | 09 Apr 2020 | 12,500 | 100,000 (0%) | 0% | 9 | 112,500 | Common Stock | |
| Charles J. Casamento | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 17 Mar 2020 | 21,484 | 40,000 (0%) | 0% | 0 | Common Stock | |
| Charles J. Casamento | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 17 Mar 2020 | 21,484 | 21,484 (0%) | 0% | 0 | Common Stock | |
| Charles J. Casamento | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2019 | 100,000 | 100,000 | - | - | Options to purchase common stock | |
| Sergio Traversa | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2019 | 350,000 | 350,000 | - | - | Options to purchase common stock | |
| Maged Shenouda | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2019 | 120,000 | 120,000 | - | - | Options to purchase common stock | |
| Paul Kelly | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2019 | 150,000 | 150,000 | - | - | Options to purchase common stock | |
| Charles S. Ence | CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2019 | 60,000 | 60,000 | - | - | Options to purchase common stock | |
| Ottavio V. Vitolo | CMO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2019 | 105,000 | 105,000 | - | - | Options to purchase common stock | |
| Maged Shenouda | Director | Purchase of securities on an exchange or from another person at price $ 23.00 per share. | 21 Oct 2019 | 978 | 2,228 (0%) | 0% | 23 | 22,494 | Common Stock |
| Paul Kelly | Director | Purchase of securities on an exchange or from another person at price $ 19.04 per share. | 18 Oct 2019 | 100 | 123,221 (0%) | 0% | 19.0 | 1,904 | Common Stock |
| Paul Kelly | Director | Purchase of securities on an exchange or from another person at price $ 19.10 per share. | 18 Oct 2019 | 200 | 123,921 (0%) | 0% | 19.1 | 3,820 | Common Stock |
| Paul Kelly | Director | Purchase of securities on an exchange or from another person at price $ 19.15 per share. | 18 Oct 2019 | 100 | 124,021 (0%) | 0% | 19.2 | 1,915 | Common Stock |
| Paul Kelly | Director | Purchase of securities on an exchange or from another person at price $ 19.20 per share. | 18 Oct 2019 | 3,100 | 127,121 (0%) | 0% | 19.2 | 59,520 | Common Stock |
| Paul Kelly | Director | Purchase of securities on an exchange or from another person at price $ 18.99 per share. | 18 Oct 2019 | 1,000 | 123,121 (0%) | 0% | 19.0 | 18,990 | Common Stock |
| Paul Kelly | Director | Purchase of securities on an exchange or from another person at price $ 19.07 per share. | 18 Oct 2019 | 400 | 123,621 (0%) | 0% | 19.1 | 7,628 | Common Stock |
| Paul Kelly | Director | Purchase of securities on an exchange or from another person at price $ 19.08 per share. | 18 Oct 2019 | 100 | 123,721 (0%) | 0% | 19.1 | 1,908 | Common Stock |
| Paul Kelly | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 12 Oct 2018 | 97,500 | 97,500 | - | - | Warrant | |
| Paul Kelly | None | Purchase of securities on an exchange or from another person at price $ 0.90 per share. | 12 Oct 2018 | 150,000 | 160,000 (1%) | 1% | 0.9 | 135,000 | Common Stock |
| Paul Kelly | None | 12 Oct 2018 | 223,483 | 383,483 (3%) | 1% | 0.7 | 160,908 | Common Stock | |
| Charles J. Casamento | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Oct 2017 | 425,000 | 425,000 | - | - | Options to purchase common stock | |
| Sergio Traversa | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Oct 2017 | 850,000 | 850,000 | - | - | Options to purchase common stock | |
| Maged Shenouda | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Oct 2017 | 425,000 | 425,000 | - | - | Options to purchase common stock | |
| Paul Kelly | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Oct 2017 | 450,000 | 450,000 | - | - | Options to purchase common stock | |
| Paul Kelly | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Oct 2017 | 200,000 | 200,000 | - | - | Convertible Note | |
| Paul Kelly | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Oct 2017 | 100,000 | 100,000 | - | - | Warrant | |
| Shreeram N. Agharkar | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 Dec 2015 | 400 | 5,759 | - | - | Common stock | |
| Shreeram N. Agharkar | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 16 Dec 2015 | 100 | 5,359 | - | - | Common stock | |
| Shreeram N. Agharkar | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 16 Dec 2015 | 1,000 | 5,259 | - | - | Common stock | |
| Sandesh Seth | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Dec 2015 | 2,500 | 120,758 | - | - | Common stock | |
| Sandesh Seth | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Dec 2015 | 2,000 | 118,258 | - | - | Common stock | |
| Sandesh Seth | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Dec 2015 | 100 | 120,858 | - | - | Common stock | |
| Sandesh Seth | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Dec 2015 | 2,500 | 116,258 | - | - | Common stock | |
| Sandesh Seth | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Dec 2015 | 2,400 | 123,258 | - | - | Common stock | |
| Sergio Traversa | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Dec 2015 | 5,600 | 331,322 | - | - | Common stock | |
| Sergio Traversa | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Dec 2015 | 200 | 337,522 | - | - | Common stock | |
| Sergio Traversa | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Dec 2015 | 2,370 | 325,722 | - | - | Common stock | |
| Sergio Traversa | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Dec 2015 | 42 | 337,322 | - | - | Common stock | |
| Sergio Traversa | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Dec 2015 | 241 | 320,593 | - | - | Common stock | |
| Sergio Traversa | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Dec 2015 | 4,358 | 335,680 | - | - | Common stock | |
| Sergio Traversa | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Dec 2015 | 1,800 | 339,322 | - | - | Common stock | |
| Sergio Traversa | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Dec 2015 | 2,759 | 323,352 | - | - | Common stock | |
| Sergio Traversa | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Dec 2015 | 1,600 | 337,280 | - | - | Common stock | |
| Maged Shenouda | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Dec 2015 | 759 | 5,000 | - | - | Common stock | |
| Maged Shenouda | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Dec 2015 | 241 | 4,241 | - | - | Common stock | |
| Maged Shenouda | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Dec 2015 | 2,000 | 4,000 | - | - | Common stock | |
| Charles J. Casamento | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 300 | 3,300 | - | - | Common stock | |
| Charles J. Casamento | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 1,300 | 3,000 | - | - | Common stock | |
| Charles J. Casamento | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 500 | 3,800 | - | - | Common stock | |
| Charles J. Casamento | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 1,700 | 1,700 | - | - | Common stock | |
| Charles J. Casamento | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 400 | 4,200 | - | - | Common stock | |
| Sandesh Seth | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 500 | 106,258 | - | - | Common stock | |
| Sandesh Seth | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 1,560 | 105,758 | - | - | Common stock | |
| Sandesh Seth | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 1,500 | 113,758 | - | - | Common stock | |
| Sandesh Seth | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 800 | 104,058 | - | - | Common stock | |
| Sandesh Seth | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 1,000 | 107,258 | - | - | Common stock | |
| Sandesh Seth | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 140 | 104,198 | - | - | Common stock | |
| Sandesh Seth | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 5,000 | 112,258 | - | - | Common stock | |
| Sergio Traversa | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 30 | 320,352 | - | - | Common stock | |
| Maged Shenouda | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 2,000 | 2,000 | - | - | Common stock | |
| Paul Kelly | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 3,000 | 8,000 | - | - | Common stock | |
| Paul Kelly | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 3,000 | 3,000 | - | - | Common stock | |
| Paul Kelly | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 1,400 | 9,400 | - | - | Common stock | |
| Paul Kelly | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 500 | 5,000 | - | - | Common stock | |
| Paul Kelly | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 1,500 | 4,500 | - | - | Common stock | |
| Paul Kelly | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Dec 2015 | 600 | 10,000 | - | - | Common stock | |
| Douglas Beck | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2015 | 25,000 | 104,437 | - | - | Options to purchase common stock | |
| Eliseo O. Salinas | President and CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2015 | 225,000 | 250,944 | - | - | Options to purchase common stock | |
| Sergio Traversa | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2015 | 225,000 | 872,745 | - | - | Options to purchase common stock |